Stage 4 breast cancer, also referred to as metastatic breast cancer, is a condition that arises when cancer cells metastasize and begin to infiltrate distant organs like the lungs, liver, bones, and even the brain. Unlike previous stages, metastatic breast cancer is known to be incurable. Although, modern medicine has managed to increase the quality and duration of life for such patients.
Focus of Treatment
As stage four confirmed breast cancer is not curable, the primary goals of treatment are:
- Control the pace at which the cancer is able to develop and spread
- Provide relief for negative symptoms to assist in making patients more comfortable
- Increase patients’ wellbeing by treating the adverse effects and allowing them to continue their daily routines Make use of normal functioning activities.
Treatment options vary depending on the existence of certain factors known to influence the type and form of treatment, these are the forms of the various subtypes of breast cancer, their spread and the patient’s overall health.
Breast Cancer Treatment Methods
1) Hormone Treatment
Hormone delicacy is useful for breast cancer that has positive hormone receptors. It is tamoxifen, anoprostrol, and aromatase inhibitors that - stop estrogen and progesterone, which propel cancer. Fulvestrant is an estrogen receptor potentially treating hormone positive cancer serving to eliminate them.
Hormones are also used with functional targeted therapies like CDK4/6 inhibitors (Palbociclib, Ribociclib) which further slows the rate of oncogenic activity.
2) Targeted Treatment
They are used to resolve properties of cancer cells at an individual basis. These include the following:
For HER2 positive breast cancer, Trastuzumab (Herceptin) and Pertuzumab, and T-DM1 are used to inhibit or block the HER2 receptor that assists in the development of cancer.
Palbociclib and Abemaciclib are CDK4/6 Inhibitor drugs that effectively slow the HR phenotype ceasable breast cancer.
PIK3CA mutations patients are benefitted by using Alpelisib PI3K inhibitors which cancels the functions of some other genes contributing to the cancer.
Olaparib and Talazoparib are the breast cancer modification with BRCA gene stunts are breast cancer gene mutation.
3. Chemotherapy
In case a patient’s cancer does not respond to hormone therapy or targeted treatment, chemotherapy is difficult to avoid as it is necessary. Chemotherapy aids in eliminating cancer cells by destroying tissue that reproduces at a faster rate. The most common chemotherapy drugs are:
- Paclitaxel (Taxol)
- Capecitabine (Xeloda)
- Doxorubicin (Adriamycin)
- Cyclophosphamide
Chemotherapy treatments are often scheduled in cycles allowing the body to heal between each episode.
4. Immunotherapy
Immunotherapy is poised to revolutionize treatment for some types of cancer, including triple-negative breast cancer (TNBC). Immusystem-enhancing agents such as Atezolizumab and Pembrolizumab aid in identifying and destroying abnormal cells and, consequently, facilitate better results for patients.
5. Radiation Therapy
For symptom relief in cases pain, and swelling where cancer has metastasized to the bones or brain, radiation therapy is often utilized. As well as in the case of controlling the growth of cancerous tissues in its early stages.
Managing Symptoms and Side Effects
Getting treatment for stage 4 breast cancer comes with a plethora of side-effects such as feeling tired, nauseous, pain, and being more vulnerable to getting sick. In order to elevate the patient’s quality of life, they are given assistance like:
- Pain Relief: Medication and alternative approaches to control discomfort.
- Physical Therapy: Treatment helps patients keep up with their range of motion and strength.
- Counseling: Emotional support through therapy and support groups.
- Nutritional Therapy: Helping with side effects of treatment by maintaining a nutritious diet.
Clinical Trials: Hope for the Future
A lot of patients that suffer from metastatic breast cancer opt unde. r clinical trials that allow participants to receive new treatments. Many new drugs and therapies are being developed for testing that aim to improve survival rates while simultaneously lowering their side effects. Discussing trial options with the oncologist can be immensely helpful when weighing if the participation would be beneficial.
Survival Rates and Outlook
Even though stage 4 breast cancer is difficult to deal with, there is a good amount of hope when it comes to further research due to the increased treatment options available that lead to improved survival rates and quality of life. Certain patients can live for years while taking care of themselves and managing the disease.
Expert Care with Dr. Pooja Babbar
Dr. Pooja Babbar, a highly experienced medical oncologist, has treated numerous breast cancer patients, providing them with compassionate, personalized care. With expertise in cutting-edge treatments like immunotherapy, targeted therapy, and precision oncology, she helps patients navigate their journey with hope and confidence. Under her guidance, many individuals have successfully managed their cancer, leading fulfilling lives despite their diagnosis.
For those facing stage 4 breast cancer, seeking the right medical support can make a significant difference. With a dedicated oncologist like Dr. Pooja Babbar, patients receive advanced treatment options tailored to their needs, ensuring the best possible outcomes.
